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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM86604'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM86604
PNG
(Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 9)
Show SMILES CN1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(OCc4ccccn4)cc3)nc12
Show InChI InChI=1S/C25H22N6O2/c1-30-21-9-4-3-8-20(21)24(32)31(2)22-15-27-25(29-23(22)30)28-17-10-12-19(13-11-17)33-16-18-7-5-6-14-26-18/h3-15H,16H2,1-2H3,(H,27,28,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 18.4n/an/an/an/an/an/a



Harvard Medical School



Assay Description
In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.

ACS Chem Biol 7: 185-96 (2012)


Article DOI: 10.1021/cb200305u
BindingDB Entry DOI: 10.7270/Q2PV6HZG
More data for this
Ligand-Target Pair