Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM155566'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM155566 (US10092556, Example 2 | US9012475, 2 | US9346787, ...) Show SMILES Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(c3F)C(F)(F)F)C(O)=O)ccc2F)n[nH]1 Show InChI InChI=1S/C24H22F5N5O3/c1-13-11-18(33-32-13)31-20-17(25)6-5-14(30-20)12-23(22(36)37)7-9-34(10-8-23)21(35)15-3-2-4-16(19(15)26)24(27,28)29/h2-6,11H,7-10,12H2,1H3,(H,36,37)(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...				US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM155566 (US10092556, Example 2 | US9012475, 2 | US9346787, ...) Show SMILES Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(c3F)C(F)(F)F)C(O)=O)ccc2F)n[nH]1 Show InChI InChI=1S/C24H22F5N5O3/c1-13-11-18(33-32-13)31-20-17(25)6-5-14(30-20)12-23(22(36)37)7-9-34(10-8-23)21(35)15-3-2-4-16(19(15)26)24(27,28)29/h2-6,11H,7-10,12H2,1H3,(H,36,37)(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	n/a
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...				US Patent US10092556 (2018) BindingDB Entry DOI: 10.7270/Q2ZG6V8B
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM155566 (US10092556, Example 2 | US9012475, 2 | US9346787, ...) Show SMILES Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(c3F)C(F)(F)F)C(O)=O)ccc2F)n[nH]1 Show InChI InChI=1S/C24H22F5N5O3/c1-13-11-18(33-32-13)31-20-17(25)6-5-14(30-20)12-23(22(36)37)7-9-34(10-8-23)21(35)15-3-2-4-16(19(15)26)24(27,28)29/h2-6,11H,7-10,12H2,1H3,(H,36,37)(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	n/a
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...				US Patent US9346787 (2016) BindingDB Entry DOI: 10.7270/Q28K77Z2
					More data for this Ligand-Target Pair