Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM155572'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM155572 (US10092556, Example 19 | US9012475, 19 | US9346787...) Show SMILES Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(Cl)c3F)C(=O)N3CCC3)ccc2F)n[nH]1 Show InChI InChI=1S/C26H27ClF2N6O2/c1-16-14-21(33-32-16)31-23-20(28)7-6-17(30-23)15-26(25(37)35-10-3-11-35)8-12-34(13-9-26)24(36)18-4-2-5-19(27)22(18)29/h2,4-7,14H,3,8-13,15H2,1H3,(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	680	n/a	n/a	n/a	n/a	7.4	n/a
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...				US Patent US9346787 (2016) BindingDB Entry DOI: 10.7270/Q28K77Z2
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM155572 (US10092556, Example 19 | US9012475, 19 | US9346787...) Show SMILES Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(Cl)c3F)C(=O)N3CCC3)ccc2F)n[nH]1 Show InChI InChI=1S/C26H27ClF2N6O2/c1-16-14-21(33-32-16)31-23-20(28)7-6-17(30-23)15-26(25(37)35-10-3-11-35)8-12-34(13-9-26)24(36)18-4-2-5-19(27)22(18)29/h2,4-7,14H,3,8-13,15H2,1H3,(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	680	n/a	n/a	n/a	n/a	7.4	n/a
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...				US Patent US10092556 (2018) BindingDB Entry DOI: 10.7270/Q2ZG6V8B
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM155572 (US10092556, Example 19 | US9012475, 19 | US9346787...) Show SMILES Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(Cl)c3F)C(=O)N3CCC3)ccc2F)n[nH]1 Show InChI InChI=1S/C26H27ClF2N6O2/c1-16-14-21(33-32-16)31-23-20(28)7-6-17(30-23)15-26(25(37)35-10-3-11-35)8-12-34(13-9-26)24(36)18-4-2-5-19(27)22(18)29/h2,4-7,14H,3,8-13,15H2,1H3,(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	880	n/a	n/a	n/a	n/a	7.4	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...				US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ
					More data for this Ligand-Target Pair