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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50053263'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM50053263
PNG
(CHEMBL3322937)
Show SMILES Oc1ccc(cc1C(=O)Nc1cccc(c1)C(F)(F)F)-n1cc(nn1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C24H13F9N4O2/c25-22(26,27)13-2-1-3-16(9-13)34-21(39)18-10-17(4-5-20(18)38)37-11-19(35-36-37)12-6-14(23(28,29)30)8-15(7-12)24(31,32)33/h1-11,38H,(H,34,39)
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Article
PubMed
n/an/a 1.38E+4n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Inhibition of Aurora B (unknown origin) using [33P]-ATP and 10 uM ATP after 2 hrs

Bioorg Med Chem 22: 4855-66 (2014)


Article DOI: 10.1016/j.bmc.2014.06.047
BindingDB Entry DOI: 10.7270/Q2PV6N11
More data for this
Ligand-Target Pair