Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B [1-341]' and Ligand = 'BDBM311132'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B [1-341] (Homo sapiens (Human))	BDBM311132 (US10155751, Example 19) Show SMILES CC(C)Cn1cc(cn1)-c1cc(O[C@H](C)[C@H]2CNC(=O)C2)c2c(C)n(C)nc2c1 |r| Show InChI InChI=1S/C22H29N5O2/c1-13(2)11-27-12-18(10-24-27)16-6-19-22(14(3)26(5)25-19)20(7-16)29-15(4)17-8-21(28)23-9-17/h6-7,10,12-13,15,17H,8-9,11H2,1-5H3,(H,23,28)/t15-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Aurora B (amino acids 1-344, clone number DU1773, Molecular weight 40.2 kDa, University of Dundee) was expressed as a fusion protei...				US Patent US10155751 (2018) BindingDB Entry DOI: 10.7270/Q2PK0J60
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