Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B-cell receptor CD22 (Homo sapiens (Human)) | BDBM50274296 (CHEMBL501599 | p-Methoxyphenyl (3,5,9-trideoxy-5-g...) | PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Antagonist activity at human CD22 after 1 hr by competitive ELISA | Bioorg Med Chem 19: 1966-71 (2011) Article DOI: 10.1016/j.bmc.2011.01.060 BindingDB Entry DOI: 10.7270/Q2QZ2B7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B-cell receptor CD22 (Homo sapiens (Human)) | BDBM50274296 (CHEMBL501599 | p-Methoxyphenyl (3,5,9-trideoxy-5-g...) | PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Binding affinity to biotinylated human CD22-human IgG1 chimeric protein expressed in mouse J558LST6 cells by flow cytometry | J Med Chem 51: 6665-81 (2008) Article DOI: 10.1021/jm8000696 BindingDB Entry DOI: 10.7270/Q23X86GN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B-cell receptor CD22 (Mus musculus) | BDBM50274296 (CHEMBL501599 | p-Methoxyphenyl (3,5,9-trideoxy-5-g...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Binding affinity to mouse CD22 after 1 hr by competition ELISA | Bioorg Med Chem Lett 19: 5573-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.044 BindingDB Entry DOI: 10.7270/Q2TH8NP3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B-cell receptor CD22 (Mus musculus) | BDBM50274296 (CHEMBL501599 | p-Methoxyphenyl (3,5,9-trideoxy-5-g...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Antagonist activity at mouse CD22 after 1 hr by competitive ELISA | Bioorg Med Chem 19: 1966-71 (2011) Article DOI: 10.1016/j.bmc.2011.01.060 BindingDB Entry DOI: 10.7270/Q2QZ2B7T | |||||||||||
More data for this Ligand-Target Pair |