Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM140562'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM140562 (US8912221, 35) Show SMILES COc1ncc(cn1)C(=O)NC1(COC1)C(=O)N[C@H](C)c1ccc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F |r| Show InChI InChI=1S/C26H23Cl2F3N4O5/c1-13(34-24(37)26(11-39-12-26)35-23(36)15-8-32-25(38-2)33-9-15)17-4-3-14(5-20(17)29)18-6-16(27)7-19(28)22(18)40-10-21(30)31/h3-9,13,21H,10-12H2,1-2H3,(H,34,37)(H,35,36)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.30	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...				US Patent US8912221 (2014) BindingDB Entry DOI: 10.7270/Q2668BWC
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