BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM50157510'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50157510 (CHEMBL225218 \| N-(4-chloro-2-{(R)-1-[3'-fluoro-2'-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]des-arg10, leu9-kallidin from human bradykinin B1 receptor expresed in CHO cells				J Med Chem 47: 6439-42 (2004) Article DOI: 10.1021/jm049394l BindingDB Entry DOI: 10.7270/Q22B8XHM
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50157510 (CHEMBL225218 \| N-(4-chloro-2-{(R)-1-[3'-fluoro-2'-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at bradykinin B1 receptor expresed in CHO cells assessed as inhibition of des-arg10-kallidin-induced increase in cytosolic calciu...				J Med Chem 47: 6439-42 (2004) Article DOI: 10.1021/jm049394l BindingDB Entry DOI: 10.7270/Q22B8XHM
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair