Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM50362324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50362324 (CHEMBL1939944) Show SMILES CN1CC[C@H](NC(=O)C[C@H]2N(C=CNC2=O)S(=O)(=O)c2cccc(Cl)c2Cl)C(C)(C)C1 |r,c:11| Show InChI InChI=1S/C20H26Cl2N4O4S/c1-20(2)12-25(3)9-7-16(20)24-17(27)11-14-19(28)23-8-10-26(14)31(29,30)15-6-4-5-13(21)18(15)22/h4-6,8,10,14,16H,7,9,11-12H2,1-3H3,(H,23,28)(H,24,27)/t14-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...				Bioorg Med Chem Lett 22: 1061-7 (2012) Article DOI: 10.1016/j.bmcl.2011.11.112 BindingDB Entry DOI: 10.7270/Q22J6CB2
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