Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'B2 bradykinin receptor' and Ligand = 'BDBM50146103'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50146103 (4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-pyrrolidin...) Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(cc(C)nc34)N3CCCC3)c2Cl)cc1 Show InChI InChI=1S/C35H35Cl2N5O4/c1-22-19-29(42-17-4-5-18-42)25-7-6-8-30(34(25)40-22)46-21-26-27(36)14-15-28(33(26)37)41(3)32(44)20-39-31(43)16-11-23-9-12-24(13-10-23)35(45)38-2/h6-16,19H,4-5,17-18,20-21H2,1-3H3,(H,38,45)(H,39,43)/b16-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co Ltd Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]BK at 1 nM to human bradykinin receptor B2 expressed in CHO cells by 50%.				J Med Chem 47: 2667-77 (2004) Article DOI: 10.1021/jm030326t BindingDB Entry DOI: 10.7270/Q2B27W2Q
					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50146103 (4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-pyrrolidin...) Show SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(cc(C)nc34)N3CCCC3)c2Cl)cc1 Show InChI InChI=1S/C35H35Cl2N5O4/c1-22-19-29(42-17-4-5-18-42)25-7-6-8-30(34(25)40-22)46-21-26-27(36)14-15-28(33(26)37)41(3)32(44)20-39-31(43)16-11-23-9-12-24(13-10-23)35(45)38-2/h6-16,19H,4-5,17-18,20-21H2,1-3H3,(H,38,45)(H,39,43)/b16-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co Ltd Curated by ChEMBL					Assay Description Inhibition of specific binding of [3H]BK at 0.06 nM to bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.				J Med Chem 47: 2667-77 (2004) Article DOI: 10.1021/jm030326t BindingDB Entry DOI: 10.7270/Q2B27W2Q
					More data for this Ligand-Target Pair