Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209081'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209081 (US9266877, 27) Show SMILES OC(=O)c1nc(ccc1-c1cn(Cc2ccccc2)nc1C#N)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C34H25N7O3S/c35-17-28-26(20-41(39-28)18-21-7-2-1-3-8-21)23-13-14-30(37-31(23)33(43)44)40-16-15-22-9-6-10-24(25(22)19-40)32(42)38-34-36-27-11-4-5-12-29(27)45-34/h1-14,20H,15-16,18-19H2,(H,43,44)(H,36,38,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	315	-37.1	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209081 (US9266877, 27) Show SMILES OC(=O)c1nc(ccc1-c1cn(Cc2ccccc2)nc1C#N)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C34H25N7O3S/c35-17-28-26(20-41(39-28)18-21-7-2-1-3-8-21)23-13-14-30(37-31(23)33(43)44)40-16-15-22-9-6-10-24(25(22)19-40)32(42)38-34-36-27-11-4-5-12-29(27)45-34/h1-14,20H,15-16,18-19H2,(H,43,44)(H,36,38,42)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair