Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209083'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209083 (US9266877, 29) Show SMILES Cc1noc(n1)-c1cccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)c1 Show InChI InChI=1S/C36H28N8O4S/c1-21-38-34(48-42-21)24-8-4-6-22(16-24)18-44-19-25(17-37-44)26-12-13-31(40-32(26)35(46)47)43-15-14-23-7-5-9-27(28(23)20-43)33(45)41-36-39-29-10-2-3-11-30(29)49-36/h2-13,16-17,19H,14-15,18,20H2,1H3,(H,46,47)(H,39,41,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	-44.2	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209083 (US9266877, 29) Show SMILES Cc1noc(n1)-c1cccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)c1 Show InChI InChI=1S/C36H28N8O4S/c1-21-38-34(48-42-21)24-8-4-6-22(16-24)18-44-19-25(17-37-44)26-12-13-31(40-32(26)35(46)47)43-15-14-23-7-5-9-27(28(23)20-43)33(45)41-36-39-29-10-2-3-11-30(29)49-36/h2-13,16-17,19H,14-15,18,20H2,1H3,(H,46,47)(H,39,41,45)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair