Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209085'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209085 (US9266877, 31) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2ccccc2OCc2ccccc2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C40H32N6O4S/c47-38(44-40-42-33-14-5-7-16-35(33)51-40)31-13-8-12-27-19-20-45(24-32(27)31)36-18-17-30(37(43-36)39(48)49)29-21-41-46(23-29)22-28-11-4-6-15-34(28)50-25-26-9-2-1-3-10-26/h1-18,21,23H,19-20,22,24-25H2,(H,48,49)(H,42,44,47)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	-44.2	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209085 (US9266877, 31) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2ccccc2OCc2ccccc2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C40H32N6O4S/c47-38(44-40-42-33-14-5-7-16-35(33)51-40)31-13-8-12-27-19-20-45(24-32(27)31)36-18-17-30(37(43-36)39(48)49)29-21-41-46(23-29)22-28-11-4-6-15-34(28)50-25-26-9-2-1-3-10-26/h1-18,21,23H,19-20,22,24-25H2,(H,48,49)(H,42,44,47)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair