Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209096'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209096 (US9266877, 42) Show SMILES OC(=O)c1nc(ccc1-c1cnn(CC2CCCCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C33H32N6O3S/c40-31(37-33-35-27-11-4-5-12-28(27)43-33)25-10-6-9-22-15-16-38(20-26(22)25)29-14-13-24(30(36-29)32(41)42)23-17-34-39(19-23)18-21-7-2-1-3-8-21/h4-6,9-14,17,19,21H,1-3,7-8,15-16,18,20H2,(H,41,42)(H,35,37,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	-49.7	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209096 (US9266877, 42) Show SMILES OC(=O)c1nc(ccc1-c1cnn(CC2CCCCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C33H32N6O3S/c40-31(37-33-35-27-11-4-5-12-28(27)43-33)25-10-6-9-22-15-16-38(20-26(22)25)29-14-13-24(30(36-29)32(41)42)23-17-34-39(19-23)18-21-7-2-1-3-8-21/h4-6,9-14,17,19,21H,1-3,7-8,15-16,18,20H2,(H,41,42)(H,35,37,40)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	233	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair