Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209098'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209098 (US9266877, 44) Show SMILES CN(C)CCCNc1ccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)cc1[N+]([O-])=O Show InChI InChI=1S/C38H37N9O5S/c1-44(2)17-6-16-39-30-13-11-24(19-32(30)47(51)52)21-46-22-26(20-40-46)27-12-14-34(42-35(27)37(49)50)45-18-15-25-7-5-8-28(29(25)23-45)36(48)43-38-41-31-9-3-4-10-33(31)53-38/h3-5,7-14,19-20,22,39H,6,15-18,21,23H2,1-2H3,(H,49,50)(H,41,43,48)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	17	-44.3	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209098 (US9266877, 44) Show SMILES CN(C)CCCNc1ccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)cc1[N+]([O-])=O Show InChI InChI=1S/C38H37N9O5S/c1-44(2)17-6-16-39-30-13-11-24(19-32(30)47(51)52)21-46-22-26(20-40-46)27-12-14-34(42-35(27)37(49)50)45-18-15-25-7-5-8-28(29(25)23-45)36(48)43-38-41-31-9-3-4-10-33(31)53-38/h3-5,7-14,19-20,22,39H,6,15-18,21,23H2,1-2H3,(H,49,50)(H,41,43,48)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair