Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209104'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209104 (US9266877, 50) Show SMILES OC(=O)c1nc(ccc1-c1cnn(CC2CCOCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C32H30N6O4S/c39-30(36-32-34-26-6-1-2-7-27(26)43-32)24-5-3-4-21-10-13-37(19-25(21)24)28-9-8-23(29(35-28)31(40)41)22-16-33-38(18-22)17-20-11-14-42-15-12-20/h1-9,16,18,20H,10-15,17,19H2,(H,40,41)(H,34,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	99	-40.0	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209104 (US9266877, 50) Show SMILES OC(=O)c1nc(ccc1-c1cnn(CC2CCOCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C32H30N6O4S/c39-30(36-32-34-26-6-1-2-7-27(26)43-32)24-5-3-4-21-10-13-37(19-25(21)24)28-9-8-23(29(35-28)31(40)41)22-16-33-38(18-22)17-20-11-14-42-15-12-20/h1-9,16,18,20H,10-15,17,19H2,(H,40,41)(H,34,36,39)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair