Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209106'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209106 (US9266877, 52) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(F)c2F)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C33H24F2N6O3S/c34-25-8-4-6-20(29(25)35)16-41-17-21(15-36-41)22-11-12-28(38-30(22)32(43)44)40-14-13-19-5-3-7-23(24(19)18-40)31(42)39-33-37-26-9-1-2-10-27(26)45-33/h1-12,15,17H,13-14,16,18H2,(H,43,44)(H,37,39,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	-44.2	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209106 (US9266877, 52) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(F)c2F)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C33H24F2N6O3S/c34-25-8-4-6-20(29(25)35)16-41-17-21(15-36-41)22-11-12-28(38-30(22)32(43)44)40-14-13-19-5-3-7-23(24(19)18-40)31(42)39-33-37-26-9-1-2-10-27(26)45-33/h1-12,15,17H,13-14,16,18H2,(H,43,44)(H,37,39,42)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair