Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209206'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209206 (US9266877, 152) Show SMILES Cc1c(cnn1C(CCN1CCOCC1)C1CCCCC1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C40H45N7O4S/c1-26-31(24-41-47(26)34(28-8-3-2-4-9-28)17-18-45-20-22-51-23-21-45)29-14-15-36(43-37(29)39(49)50)46-19-16-27-10-7-11-30(32(27)25-46)38(48)44-40-42-33-12-5-6-13-35(33)52-40/h5-7,10-15,24,28,34H,2-4,8-9,16-23,25H2,1H3,(H,49,50)(H,42,44,48)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	<-57.1	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209206 (US9266877, 152) Show SMILES Cc1c(cnn1C(CCN1CCOCC1)C1CCCCC1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C40H45N7O4S/c1-26-31(24-41-47(26)34(28-8-3-2-4-9-28)17-18-45-20-22-51-23-21-45)29-14-15-36(43-37(29)39(49)50)46-19-16-27-10-7-11-30(32(27)25-46)38(48)44-40-42-33-12-5-6-13-35(33)52-40/h5-7,10-15,24,28,34H,2-4,8-9,16-23,25H2,1H3,(H,49,50)(H,42,44,48)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair