Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327]' and Ligand = 'BDBM449749'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human))	BDBM449749 (US10703733, Example 362 | US10988451, Example 362 ...) Show SMILES COC1CN(C1)C(=O)N[S@@]1(=O)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@@H](OC)\C=C\C[C@H](C)C1)c3c2 |r,t:45| Show InChI InChI=1S/C37H47ClN4O6S/c1-24-6-4-8-33(47-3)30-12-9-27(30)18-42-22-37(15-5-7-25-16-28(38)11-13-31(25)37)23-48-34-14-10-26(17-32(34)42)35(43)39-49(45,21-24)40-36(44)41-19-29(20-41)46-2/h4,8,10-11,13-14,16-17,24,27,29-30,33H,5-7,9,12,15,18-23H2,1-3H3,(H,39,40,43,44,45)/b8-4+/t24-,27-,30+,33-,37-,49-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q24B357N
					More data for this Ligand-Target Pair
Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human))	BDBM449749 (US10703733, Example 362 | US10988451, Example 362 ...) Show SMILES COC1CN(C1)C(=O)N[S@@]1(=O)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@@H](OC)\C=C\C[C@H](C)C1)c3c2 |r,t:45| Show InChI InChI=1S/C37H47ClN4O6S/c1-24-6-4-8-33(47-3)30-12-9-27(30)18-42-22-37(15-5-7-25-16-28(38)11-13-31(25)37)23-48-34-14-10-26(17-32(34)42)35(43)39-49(45,21-24)40-36(44)41-19-29(20-41)46-2/h4,8,10-11,13-14,16-17,24,27,29-30,33H,5-7,9,12,15,18-23H2,1-3H3,(H,39,40,43,44,45)/b8-4+/t24-,27-,30+,33-,37-,49-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0240	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...				US Patent US10703733 (2020) BindingDB Entry DOI: 10.7270/Q2XK8JK4
					More data for this Ligand-Target Pair