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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 11 [72-87]' and Ligand = 'BDBM361578'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 11 [72-87]


(Homo sapiens (Human))		BDBM361578
PNG
(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Show SMILES [O-][N+](=O)c1cc(ccc1NCC1CCOCC1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)C1=CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1 |t:44,49|
Show InChI InChI=1S/C47H49ClN6O7S/c48-37-5-2-33(3-6-37)41-27-47(16-1-17-47)18-10-36(41)30-53-20-12-32(13-21-53)34-4-8-40(44(25-34)61-38-24-35-11-19-49-45(35)51-29-38)46(55)52-62(58,59)39-7-9-42(43(26-39)54(56)57)50-28-31-14-22-60-23-15-31/h2-9,11-12,19,24-26,29,31,50H,1,10,13-18,20-23,27-28,30H2,(H,49,51)(H,52,55)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40n/an/an/an/an/an/a



THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent


Assay Description
Bcl-2 and Bcl-xL Inhibition: Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respect...

US Patent US10829488 (2020)


BindingDB Entry DOI: 10.7270/Q28D00BQ
More data for this
Ligand-Target Pair