BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM50096784'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (Human))		BDBM50096784
PNG
(CHEMBL332010 | Cyanoguanidine derivative)
Show SMILES NC(=O)c1cccc(NC(Nc2ccc(CCNC[C@H](O)c3cccnc3)cc2)=NC#N)c1 |w:29.31|
Show InChI InChI=1S/C24H25N7O2/c25-16-29-24(31-21-5-1-3-18(13-21)23(26)33)30-20-8-6-17(7-9-20)10-12-28-15-22(32)19-4-2-11-27-14-19/h1-9,11,13-14,22,28,32H,10,12,15H2,(H2,26,33)(H2,29,30,31)/t22-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 980n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for human Beta-1 adrenergic receptor using [125I]-iodocyanopindolol as radioligand in CHO cells

Bioorg Med Chem Lett 11: 379-82 (2001)


BindingDB Entry DOI: 10.7270/Q2CR5SNJ
More data for this
Ligand-Target Pair