Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Staphylococcus aureus) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureus | Bioorg Med Chem Lett 10: 847-51 (2000) BindingDB Entry DOI: 10.7270/Q2NG4PVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacae | Bioorg Med Chem Lett 10: 853-7 (2000) BindingDB Entry DOI: 10.7270/Q2HQ3Z41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 943 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae P99 | J Med Chem 38: 1022-34 (1995) BindingDB Entry DOI: 10.7270/Q29S1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Escherichia coli) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 950 | n/a | n/a | n/a | n/a | 7.0 | n/a |
MEIJI SEIKA PHARMA CO., LTD. US Patent | Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D... | US Patent US9035062 (2015) BindingDB Entry DOI: 10.7270/Q2KP80XX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Staphylococcus aureus) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description The compound was evaluated for inhibition against Beta-lactamase derived from Staphylococcus aureus | Bioorg Med Chem Lett 10: 847-51 (2000) BindingDB Entry DOI: 10.7270/Q2NG4PVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Staphylococcus aureus) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1 | Bioorg Med Chem Lett 10: 853-7 (2000) BindingDB Entry DOI: 10.7270/Q2HQ3Z41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99 | Bioorg Med Chem Lett 10: 853-7 (2000) BindingDB Entry DOI: 10.7270/Q2HQ3Z41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae SC 12368 | J Med Chem 38: 1022-34 (1995) BindingDB Entry DOI: 10.7270/Q29S1Q29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Escherichia coli) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against AmpC (class C) beta-lactamase | Bioorg Med Chem Lett 9: 997-1002 (1999) BindingDB Entry DOI: 10.7270/Q2PK0FBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Escherichia coli) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibitory activity of the compound against AmpC (class C) beta-lactamase | Bioorg Med Chem Lett 9: 991-6 (1999) BindingDB Entry DOI: 10.7270/Q2TB163Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description The compound was evaluated for inhibition against Class C beta-lactamase derived from Enterobacter cloacae P99 | Bioorg Med Chem Lett 10: 853-7 (2000) BindingDB Entry DOI: 10.7270/Q2HQ3Z41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description Inhibition of Class C beta-lactamase from E. cloacae strain P99 | Bioorg Med Chem Lett 10: 847-51 (2000) BindingDB Entry DOI: 10.7270/Q2NG4PVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Escherichia coli) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University Curated by ChEMBL | Assay Description Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzyme | Bioorg Med Chem Lett 14: 1299-304 (2004) Article DOI: 10.1016/j.bmcl.2003.12.037 BindingDB Entry DOI: 10.7270/Q22Z14ZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Enterobacter cloacae) | BDBM50157692 (CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of Enterobacter cloacae AmpC | J Med Chem 47: 6556-68 (2004) Article DOI: 10.1021/jm049680x BindingDB Entry DOI: 10.7270/Q2542N22 | |||||||||||
More data for this Ligand-Target Pair |