Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM136548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM136548 (US8865701, 21 | US9505739, 21) Show SMILES O=C([C@@H]1CNC[C@]11CCc2ccccc12)N1CC[C@H](C[C@H]1c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C30H32N2O/c33-29(27-20-31-21-30(27)17-15-23-11-7-8-14-26(23)30)32-18-16-25(22-9-3-1-4-10-22)19-28(32)24-12-5-2-6-13-24/h1-14,25,27-28,31H,15-21H2/t25-,27+,28+,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US9505739 (2016) BindingDB Entry DOI: 10.7270/Q2C53JST
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM136548 (US8865701, 21 | US9505739, 21) Show SMILES O=C([C@@H]1CNC[C@]11CCc2ccccc12)N1CC[C@H](C[C@H]1c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C30H32N2O/c33-29(27-20-31-21-30(27)17-15-23-11-7-8-14-26(23)30)32-18-16-25(22-9-3-1-4-10-22)19-28(32)24-12-5-2-6-13-24/h1-14,25,27-28,31H,15-21H2/t25-,27+,28+,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	6.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...				US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1
					More data for this Ligand-Target Pair