Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM147148'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM147148 (US8957083, 8) Show SMILES COc1ccc2Oc3ccc(cc3[C@@]3(N=C(N)N(C)C3=O)c2c1)-c1cncnc1 |r,t:15| Show InChI InChI=1S/C21H17N5O3/c1-26-19(27)21(25-20(26)22)15-7-12(13-9-23-11-24-10-13)3-5-17(15)29-18-6-4-14(28-2)8-16(18)21/h3-11H,1-2H3,(H2,22,25)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13.4	n/a	n/a	n/a	n/a	4.2	n/a
Amgen Inc. US Patent					Assay Description The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...				US Patent US8957083 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TS5
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