Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM147187'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM147187 (US8957083, 40) Show SMILES COc1ccc2Oc3ccc(NC(=O)c4ccc(Cl)cn4)cc3C3(N=C(N)N(C)C3=O)c2c1 |t:26| Show InChI InChI=1S/C23H18ClN5O4/c1-29-21(31)23(28-22(29)25)15-9-13(27-20(30)17-6-3-12(24)11-26-17)4-7-18(15)33-19-8-5-14(32-2)10-16(19)23/h3-11H,1-2H3,(H2,25,28)(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	4.2	n/a
Amgen Inc. US Patent					Assay Description The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...				US Patent US8957083 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TS5
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