Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM149268'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM149268 (US8962674, CU249) Show SMILES COc1cccc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2)c1O Show InChI InChI=1S/C20H18O5/c1-25-19-4-2-3-15(20(19)24)8-12-18(23)13-17(22)11-7-14-5-9-16(21)10-6-14/h2-12,21,24H,13H2,1H3/b11-7+,12-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	4.5	37
Tokyo Institute of Technology; Kyoto University US Patent					Assay Description Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...				US Patent US8962674 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G1J
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