Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM171656'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM171656 (US9085576, 290 | US9611261, Example 290) Show SMILES NC1=N[C@@](C(F)F)([C@H]2C[C@H]2O1)c1cc(NC(=O)c2ncc(Br)cc2C(F)F)ccc1F |r,t:1| Show InChI InChI=1S/C19H14BrF5N4O2/c20-7-3-9(15(22)23)14(27-6-7)16(30)28-8-1-2-12(21)10(4-8)19(17(24)25)11-5-13(11)31-18(26)29-19/h1-4,6,11,13,15,17H,5H2,(H2,26,29)(H,28,30)/t11-,13+,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...				US Patent US9611261 (2017) BindingDB Entry DOI: 10.7270/Q21J9CW2
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM171656 (US9085576, 290 | US9611261, Example 290) Show SMILES NC1=N[C@@](C(F)F)([C@H]2C[C@H]2O1)c1cc(NC(=O)c2ncc(Br)cc2C(F)F)ccc1F |r,t:1| Show InChI InChI=1S/C19H14BrF5N4O2/c20-7-3-9(15(22)23)14(27-6-7)16(30)28-8-1-2-12(21)10(4-8)19(17(24)25)11-5-13(11)31-18(26)29-19/h1-4,6,11,13,15,17H,5H2,(H2,26,29)(H,28,30)/t11-,13+,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14.1	n/a	n/a	n/a	n/a	4.2	n/a
AMGEN INC. US Patent					Assay Description The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...				US Patent US9085576 (2015) BindingDB Entry DOI: 10.7270/Q2CF9NWF
					More data for this Ligand-Target Pair