Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM239000'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM239000 (US9403846, 14) Show SMILES NC1=N[C@]2(CO[C@H](C[C@H]2CS1)C1CC1)c1ccccc1 |t:1| Show InChI InChI=1S/C16H20N2OS/c17-15-18-16(12-4-2-1-3-5-12)10-19-14(11-6-7-11)8-13(16)9-20-15/h1-5,11,13-14H,6-10H2,(H2,17,18)/t13-,14+,16+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	4.5	n/a
Pfizer Inc. US Patent					Assay Description A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...				US Patent US9403846 (2016) BindingDB Entry DOI: 10.7270/Q2JW8CTW
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