BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50141552'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))		BDBM50141552
PNG
(3-[(S)-3-((S)-2-{(S)-2-[2-Amino-3-((S)-carboxyamin...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CNC(O)=O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)Nc1cccc(c1)C(O)=O
Show InChI InChI=1S/C32H44N6O9/c1-17(2)13-24(37-29(42)25(18(3)4)38-27(40)22(33)16-34-32(46)47)28(41)36-23(14-19-9-6-5-7-10-19)26(39)30(43)35-21-12-8-11-20(15-21)31(44)45/h5-12,15,17-18,22-26,34,39H,13-14,16,33H2,1-4H3,(H,35,43)(H,36,41)(H,37,42)(H,38,40)(H,44,45)(H,46,47)/t22-,23-,24-,25-,26+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Kyoto Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibitory concentration of compound against Beta-secretase 1 was evaluated

Bioorg Med Chem Lett 14: 1527-31 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.088
BindingDB Entry DOI: 10.7270/Q2V987H4
More data for this
Ligand-Target Pair