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Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM172734'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-secretase 2


(Homo sapiens (Human))		BDBM172734
PNG
(US9096541, 1910)
Show SMILES CSC[C@H](NC(=O)C1NOC2OCCC12)C(=O)NC(CC(C)C)[C@@H](O)CC(C)C(=O)NC(C(C)C)C(=O)N(C)C |r|
Show InChI InChI=1S/C27H49N5O7S/c1-14(2)11-18(20(33)12-16(5)23(34)30-21(15(3)4)26(37)32(6)7)28-24(35)19(13-40-8)29-25(36)22-17-9-10-38-27(17)39-31-22/h14-22,27,31,33H,9-13H2,1-8H3,(H,28,35)(H,29,36)(H,30,34)/t16?,17?,18?,19-,20-,21?,22?,27?/m0/s1
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Similars
US Patent
 46n/an/an/an/an/an/an/an/a



Oklahoma Medical Research Foundation; Purdue Research Foundation

US Patent


Assay Description
Previously, one of the following compounds discussed below have been studied in memapsin 2 inhibition (Ghosh et al., 2008), which the others are prev...

US Patent US9096541 (2015)


BindingDB Entry DOI: 10.7270/Q2TH8KF4
More data for this
Ligand-Target Pair