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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50558211'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bifunctional epoxide hydrolase 2


(Homo sapiens (Human))
BDBM50558211
PNG
(CHEMBL2332114)
Show SMILES [H][C@@]1(O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2ccc(cc2OC)-c2oc3cc(OC)cc(O)c3c(=O)c2OC)OC[C@](O)(CO)[C@H]1O |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.82E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Non competitive inhibition of sEH (unknown origin) using varying levels of PHOME as substrate by Dixon plot analysis


Citation and Details

Article DOI: 10.1016/j.bmc.2016.05.034
BindingDB Entry DOI: 10.7270/Q2833WP0
More data for this
Ligand-Target Pair
Bifunctional epoxide hydrolase 2


(Homo sapiens (Human))
BDBM50558211
PNG
(CHEMBL2332114)
Show SMILES [H][C@@]1(O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2ccc(cc2OC)-c2oc3cc(OC)cc(O)c3c(=O)c2OC)OC[C@](O)(CO)[C@H]1O |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of sEH (unknown origin) assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate measured after 40 mins by f...


Citation and Details

Article DOI: 10.1016/j.bmc.2016.05.034
BindingDB Entry DOI: 10.7270/Q2833WP0
More data for this
Ligand-Target Pair