Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial' and Ligand = 'BDBM581292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (Homo sapiens (Human))	BDBM581292 ((2S)-2-({5-[2-(2,4-diamino-6-oxo- 1,6-dihydropyrim...) Show SMILES Nc1nc(N)c(CC(=O)Nc2cnc(C(=O)N[C@@H](CCC(O)=O)C(O)=O)c(F)c2)c(=O)[nH]1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To determine the IC50 value of a compound, an 11-concentration dose-response curve with 3-fold difference in concentration between assay points was g...				Citation and Details BindingDB Entry DOI: 10.7270/Q2P84GRR
					More data for this Ligand-Target Pair