Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase' and Ligand = 'BDBM489192'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (Human)	BDBM489192 (US10961233, Example 33) Show SMILES CN(C)CCOC(=O)N1CCN(CC1)c1ccc(Cl)c(NC(=O)c2coc(N)n2)c1 Show InChI InChI=1S/C19H25ClN6O4/c1-24(2)9-10-29-19(28)26-7-5-25(6-8-26)13-3-4-14(20)15(11-13)22-17(27)16-12-30-18(21)23-16/h3-4,11-12H,5-10H2,1-2H3,(H2,21,23)(H,22,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.5	n/a	n/a	n/a	n/a	n/a	n/a
LIFEARC US Patent					Assay Description 5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...				US Patent US10961233 (2021) BindingDB Entry DOI: 10.7270/Q2R214HW
					More data for this Ligand-Target Pair