Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase' and Ligand = 'BDBM489194'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (Human)	BDBM489194 (US10961233, Example 35) Show SMILES Nc1nc(co1)C(=O)Nc1cc(ccc1Cl)N1CCN(CC1)C(=O)OCCNC1CC1 Show InChI InChI=1S/C20H25ClN6O4/c21-15-4-3-14(11-16(15)24-18(28)17-12-31-19(22)25-17)26-6-8-27(9-7-26)20(29)30-10-5-23-13-1-2-13/h3-4,11-13,23H,1-2,5-10H2,(H2,22,25)(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.5	n/a	n/a	n/a	n/a	n/a	n/a
LIFEARC US Patent					Assay Description 5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...				US Patent US10961233 (2021) BindingDB Entry DOI: 10.7270/Q2R214HW
					More data for this Ligand-Target Pair