Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase' and Ligand = 'BDBM489215'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (Human)	BDBM489215 (US10961233, Example 70) Show SMILES CCNCCCS(=O)(=O)N1CCN(CC1)c1ccc(Br)c(NC(=O)c2coc(N)n2)c1 Show InChI InChI=1S/C19H27BrN6O4S/c1-2-22-6-3-11-31(28,29)26-9-7-25(8-10-26)14-4-5-15(20)16(12-14)23-18(27)17-13-30-19(21)24-17/h4-5,12-13,22H,2-3,6-11H2,1H3,(H2,21,24)(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
LIFEARC US Patent					Assay Description 5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...				US Patent US10961233 (2021) BindingDB Entry DOI: 10.7270/Q2R214HW
					More data for this Ligand-Target Pair