Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase' and Ligand = 'BDBM489226'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (Human)	BDBM489226 (US10961233, Example 87) Show SMILES CN1CCC(CC1)S(=O)(=O)N1CCN(CC1)c1ccc(Cl)c(NC(=O)c2coc(N)n2)c1 Show InChI InChI=1S/C20H27ClN6O4S/c1-25-6-4-15(5-7-25)32(29,30)27-10-8-26(9-11-27)14-2-3-16(21)17(12-14)23-19(28)18-13-31-20(22)24-18/h2-3,12-13,15H,4-11H2,1H3,(H2,22,24)(H,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
LIFEARC US Patent					Assay Description 5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...				US Patent US10961233 (2021) BindingDB Entry DOI: 10.7270/Q2R214HW
					More data for this Ligand-Target Pair