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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional purine biosynthesis protein ATIC' and Ligand = 'BDBM92371'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bifunctional purine biosynthesis protein ATIC


(Homo sapiens (Human))		BDBM92371
PNG
(RY Analogue, 11)
Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8]-[#6])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O |r|
Show InChI InChI=1S/C20H32N6O4/c1-4-23-18(28)17(12-14-7-9-15(30-3)10-8-14)26-19(29)16(25-13(2)27)6-5-11-24-20(21)22/h7-10,16-17H,4-6,11-12H2,1-3H3,(H,23,28)(H,25,27)(H,26,29)(H4,21,22,24)/t16-,17-/m0/s1
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Similars
Article
PubMed
 8.70E+4 -23.2n/an/an/an/an/an/a25



University of Southampton



Assay Description
Enzyme inhibition using aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).

Chembiochem 13: 1628-34 (2012)


Article DOI: 10.1002/cbic.201200279
BindingDB Entry DOI: 10.7270/Q2P26WQZ
More data for this
Ligand-Target Pair