Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bifunctional purine biosynthesis protein ATIC' and Ligand = 'BDBM92374'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM92374 (RY Analogue, 14) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)N(=O)=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O |r| Show InChI InChI=1S/C19H29N7O5/c1-3-22-17(28)16(11-13-6-8-14(9-7-13)26(30)31)25-18(29)15(24-12(2)27)5-4-10-23-19(20)21/h6-9,15-16H,3-5,10-11H2,1-2H3,(H,22,28)(H,24,27)(H,25,29)(H4,20,21,23)/t15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	685	-35.2	n/a	n/a	n/a	n/a	n/a	n/a	25
University of Southampton					Assay Description Enzyme inhibition using aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).				Chembiochem 13: 1628-34 (2012) Article DOI: 10.1002/cbic.201200279 BindingDB Entry DOI: 10.7270/Q2P26WQZ
					More data for this Ligand-Target Pair