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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50028475'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bile acid receptor


(Homo sapiens (Human))		BDBM50028475
PNG
(CHEMBL3335673)
Show SMILES Cc1ccc(NC(=O)c2ccc(Cl)cc2NC(=O)c2ccc(cc2)C(C)(C)C)cc1C(O)=O
Show InChI InChI=1S/C26H25ClN2O4/c1-15-5-11-19(14-21(15)25(32)33)28-24(31)20-12-10-18(27)13-22(20)29-23(30)16-6-8-17(9-7-16)26(2,3)4/h5-14H,1-4H3,(H,28,31)(H,29,30)(H,32,33)
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Similars
Article
PubMed
n/an/an/an/a 110n/an/an/an/a



Goethe University Frankfurt

Curated by ChEMBL


Assay Description
Agonist activity at human FXR expressed in human HeLa cells assessed as receptor activation by BSEP promoter-driven firefly luciferase reporter gene ...

J Med Chem 57: 8035-55 (2014)


Article DOI: 10.1021/jm500937v
BindingDB Entry DOI: 10.7270/Q26H4K06
More data for this
Ligand-Target Pair