Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bone morphogenetic protein receptor type-1A [198-525]' and Ligand = 'BDBM451796'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bone morphogenetic protein receptor type-1A [198-525] (Homo sapiens (Human))	BDBM451796 (US10710980, Example 28 | US10947218, Example 28) Show SMILES Nc1ncc(cc1C(=O)NC12CC(CO)(C1)C2)-c1ccc(cc1)[C@]12C[C@H]1CN(C2)C1CCOCC1 |r| Show InChI InChI=1S/C28H34N4O3/c29-24-23(25(34)31-27-13-26(14-27,15-27)17-33)9-19(11-30-24)18-1-3-20(4-2-18)28-10-21(28)12-32(16-28)22-5-7-35-8-6-22/h1-4,9,11,21-22,33H,5-8,10,12-17H2,(H2,29,30)(H,31,34)/t21-,26?,27?,28+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description A kinase selectivity panel which measures autophosphorylation using the ADP-Glo Kinase Assay (Promega, V9101) was set-up for wild-type ALK2 (aa172-49...				US Patent US10947218 (2021) BindingDB Entry DOI: 10.7270/Q24F1TVV
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1A [198-525] (Homo sapiens (Human))	BDBM451796 (US10710980, Example 28 | US10947218, Example 28) Show SMILES Nc1ncc(cc1C(=O)NC12CC(CO)(C1)C2)-c1ccc(cc1)[C@]12C[C@H]1CN(C2)C1CCOCC1 |r| Show InChI InChI=1S/C28H34N4O3/c29-24-23(25(34)31-27-13-26(14-27,15-27)17-33)9-19(11-30-24)18-1-3-20(4-2-18)28-10-21(28)12-32(16-28)22-5-7-35-8-6-22/h1-4,9,11,21-22,33H,5-8,10,12-17H2,(H2,29,30)(H,31,34)/t21-,26?,27?,28+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were generated by ...				US Patent US10710980 (2020) BindingDB Entry DOI: 10.7270/Q2DF6V81
					More data for this Ligand-Target Pair