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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 [60-463]' and Ligand = 'BDBM274236'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 2 [60-463]


(Homo sapiens (Human))		BDBM274236
PNG
(6-(4-chlorophenyl)-5-(3,8-di methyl-[1,2,4]triazol...)
Show SMILES Cc1cn(C)c2C(N(C(=O)c12)c1cc(C)c2nnc(C)n2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H20ClN5O/c1-12-9-17(11-27-14(3)24-25-21(12)27)28-19(15-5-7-16(23)8-6-15)20-18(22(28)29)13(2)10-26(20)4/h5-11,19H,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 36n/an/an/an/a7.5n/a



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...

US Patent US9550796 (2017)


BindingDB Entry DOI: 10.7270/Q2QN68SK
More data for this
Ligand-Target Pair