Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 [60-463]' and Ligand = 'BDBM274261'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 [60-463] (Homo sapiens (Human))	BDBM274261 (6-(4-chlorophenyl)-5-(1,5-dimethyl-6-oxo-1,6-dihyd...) Show SMILES COc1ccc(cn1)-c1cc2C(=O)N(C(c2n1C)c1ccc(Cl)cc1)c1cc(C)c(=O)n(C)c1 Show InChI InChI=1S/C26H23ClN4O3/c1-15-11-19(14-29(2)25(15)32)31-23(16-5-8-18(27)9-6-16)24-20(26(31)33)12-21(30(24)3)17-7-10-22(34-4)28-13-17/h5-14,23H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9550796 (2017) BindingDB Entry DOI: 10.7270/Q2QN68SK
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