Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM320305'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320305 (2-{4-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-methane...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1c(ccc(N3CCN(CC(N)=O)CC3)c21)S(C)(=O)=O |r| Show InChI InChI=1S/C34H40N8O4S/c1-22-32(39(2)38-37-22)25-19-27-31(36-20-25)30-26(41-15-13-40(14-16-41)21-29(35)43)9-10-28(47(3,44)45)34(30)42(27)33(23-7-5-4-6-8-23)24-11-17-46-18-12-24/h4-10,19-20,24,33H,11-18,21H2,1-3H3,(H2,35,43)/t33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair