Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM320322'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320322 (4-{5-[(S)-(4-Fluorophenyl)(oxan-4-yl)methyl]-3-[4-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccc(F)cc1)c1ccc(cc21)N1CCS(=O)(=O)CC1 |r| Show InChI InChI=1S/C31H33FN6O3S/c1-20-30(36(2)35-34-20)23-17-28-29(33-19-23)26-18-25(37-11-15-42(39,40)16-12-37)7-8-27(26)38(28)31(22-9-13-41-14-10-22)21-3-5-24(32)6-4-21/h3-8,17-19,22,31H,9-16H2,1-2H3/t31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair