Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM320325'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320325 (1-{5-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-3-[4-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1F)c1ccc(cc21)N1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C32H36FN7O3S/c1-21-31(37(2)36-35-21)23-18-29-30(34-20-23)26-19-24(38-12-14-39(15-13-38)44(3,41)42)8-9-28(26)40(29)32(22-10-16-43-17-11-22)25-6-4-5-7-27(25)33/h4-9,18-20,22,32H,10-17H2,1-3H3/t32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair