Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM320355'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320355 (1-{5-[(4,4-Difluorocyclohexyl)(phenyl)methyl]-6-me...) Show SMILES Cc1[nH]nn(C)c1-c1cnc2c(c1)n(C(C1CCC(F)(F)CC1)c1ccccc1)c1c(C)ccc(N3CCC(F)(F)CC3)c21 Show InChI InChI=1S/C34H36F4N6/c1-21-9-10-26(43-17-15-34(37,38)16-18-43)28-29-27(19-25(20-39-29)31-22(2)40-41-42(31)3)44(30(21)28)32(23-7-5-4-6-8-23)24-11-13-33(35,36)14-12-24/h4-10,19-20,24,32H,11-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320355 (1-{5-[(4,4-Difluorocyclohexyl)(phenyl)methyl]-6-me...) Show SMILES Cc1[nH]nn(C)c1-c1cnc2c(c1)n(C(C1CCC(F)(F)CC1)c1ccccc1)c1c(C)ccc(N3CCC(F)(F)CC3)c21 Show InChI InChI=1S/C34H36F4N6/c1-21-9-10-26(43-17-15-34(37,38)16-18-43)28-29-27(19-25(20-39-29)31-22(2)40-41-42(31)3)44(30(21)28)32(23-7-5-4-6-8-23)24-11-13-33(35,36)14-12-24/h4-10,19-20,24,32H,11-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair