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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50180983'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50180983
PNG
(CHEMBL3819533)
Show SMILES Cc1noc(C)c1-c1cc(OCCCCCCC(=O)NO)cc(c1)C(O)c1ccccc1
Show InChI InChI=1S/C25H30N2O5/c1-17-24(18(2)32-27-17)20-14-21(25(29)19-10-6-5-7-11-19)16-22(15-20)31-13-9-4-3-8-12-23(28)26-30/h5-7,10-11,14-16,25,29-30H,3-4,8-9,12-13H2,1-2H3,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 770n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human BRD4 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 by bromodomain alphascreen peptide displacement assay

Bioorg Med Chem Lett 26: 2931-2935 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.034
BindingDB Entry DOI: 10.7270/Q2MW2K2V
More data for this
Ligand-Target Pair