Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50276614'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50276614 (CHEMBL4167421) Show SMILES COc1ccccc1CN1C(C)C(=O)N(C)c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc12 Show InChI InChI=1S/C25H27N3O4S/c1-17-9-12-21(13-10-17)33(30,31)26-20-11-14-22-23(15-20)28(18(2)25(29)27(22)3)16-19-7-5-6-8-24(19)32-4/h5-15,18,26H,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JQ1-FITC binding to His6-tagged BRD4-BD1 (unknown origin) expressed in Escherichia coli BL21 (DE3)-codon plus-RIL cells incubated in da...				Eur J Med Chem 137: 176-195 (2017) Article DOI: 10.1016/j.ejmech.2017.05.049 BindingDB Entry DOI: 10.7270/Q2X069J5
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