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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [368-440]' and Ligand = 'BDBM333407'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [368-440]


(Homo sapiens (Human))		BDBM333407
PNG
(4-[6-(2,4-Difluorophenoxy)-1-methyl-1H-benzimidazo...)
Show SMILES Cn1cnc2cc(c(Oc3ccc(F)cc3F)cc12)-c1cn(C)c(=O)c2[nH]ccc12
Show InChI InChI=1S/C22H16F2N4O2/c1-27-10-15(13-5-6-25-21(13)22(27)29)14-8-17-18(28(2)11-26-17)9-20(14)30-19-4-3-12(23)7-16(19)24/h3-11,25H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...

US Patent US9737516 (2017)


BindingDB Entry DOI: 10.7270/Q2154K40
More data for this
Ligand-Target Pair