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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [368-440]' and Ligand = 'BDBM333426'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [368-440]


(Homo sapiens (Human))		BDBM333426
PNG
(Ammonium 3-[5-(cyclobutylmethoxy)-6-(6-methyl-7-ox...)
Show SMILES Cn1cc(-c2cc3[nH]c(CCC([O-])=O)nc3cc2OCC2CCC2)c2cc[nH]c2c1=O
Show InChI InChI=1S/C23H24N4O4/c1-27-11-16(14-7-8-24-22(14)23(27)30)15-9-17-18(26-20(25-17)5-6-21(28)29)10-19(15)31-12-13-3-2-4-13/h7-11,13,24H,2-6,12H2,1H3,(H,25,26)(H,28,29)/p-1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...

US Patent US9737516 (2017)


BindingDB Entry DOI: 10.7270/Q2154K40
More data for this
Ligand-Target Pair